Morphinan alkaloids in Papaver bracteatum: Biosynthesis and fate

Selective Reduction of Morphinan Alkaloids

Determination of alkaloids amount from Iranian Papaver bracteatum Lindl. by HPLC

Background & Aim: Papaver bracteatum Lindl.  (Papaverace) is an important pharmaceutical plant which contains isoqinoline alkaloids. Isoqinoline alkaloids constitute one distinct group of secondary metabolites of the Papaverace family. Codeine and thebaine are important alkaloids of Papaver bracteatum which use widely due to its medicinal properties. Therefore it is...

Synthesis of Morphinan Alkaloids in Saccharomyces cerevisiae

Morphinan alkaloids are the most powerful narcotic analgesics currently used to treat moderate to severe and chronic pain. The feasibility of morphinan synthesis in recombinant Saccharomyces cerevisiae starting from the precursor (R,S)-norlaudanosoline was investigated. Chiral analysis of the reticuline produced by the expression of opium poppy methyltransferases showed strict enantioselectivit...

Determination of alkaloids amount from Iranian Papaver bracteatum Lindl. by HPLC

Background & Aim: Papaver bracteatum Lindl.  (Papaverace) is an important pharmaceutical plant which contains isoqinoline alkaloids. Isoqinoline alkaloids constitute one distinct group of secondary metabolites of the Papaverace family. Codeine and thebaine are important alkaloids of Papaver bracteatum which use widely due to its medicinal properties. Therefore it is...

ALKALOIDS OF PAPAVERACEAE (XIII).' ALKALOIDS OF PAPAVER F UGAX POPULATION KHALKHAL AND PAPAVER CA UCASICUM POPULATION ELIKA

Papaver fugax Poiret population Khalkhal was shown to contain four major alkaloids, roemerine (0.19%), mecamberine (0.39%), liriodenine (0.20%) and salutaridine (0.10%). Papaver caucasicum M. B. population Elika was shown to contain four major alkaloids, nuciferine (0.50%), amurensinine (0.15%), lysicamine (0.30%) and nornuciferine (0.40%). Lysicarnine and nornuciferine were detected for t...